Anti TPO antibodies test is a common test for the diagnosis of thyroid disorders. In autoimmune diseases of thyroid glands, the patient’s immune system makes antibodies that mistakenly attack normal tissue of thyroid glands. The Anti-TPO antibodies attacking the thyroid gland cause swelling, rarely tenderness and reduced normal functioning of the thyroid. Anti TPO test prices range from Rs 600 to Rs 1300 in India.
Anti TPO test detects the autoimmune disorders of thyroid glands such as Graves’ disease or Hashimoto’s disease. TPO (Thyroid peroxidase) enzyme is crucial in producing thyroid hormones T3 and T4. These hormones regulate growth and development in the human body. Thus, high Anti TPO antibodies in the blood may indicate a thyroid disorder.
| Also known as | Anti TPO Antibodies test, Thyroid peroxidase antibody test, TPO antibody test, Antithyroid antibodies test, AMA Test |
| Purpose | Diagnosis of Hashimoto’s disease or Graves’ disease, hypothyroidism |
| Preparation | Avoid multivitamins or dietary supplements containing biotin (vitamin B7). |
| Fasting required | No fasting is required. |
| Reporting time | 8 to 24 hours |
| Cost | Rs 600 to Rs 1300 |
Anti-TPO test price depends on diagnostic centres and cities. However, it usually ranges from Rs 600 to Rs 1300 in India.
The table below lists the Anti-TPO antibodies test prices for major diagnostic centres in India.
| Diagnostic centers | Price |
|---|---|
| Metropolis Healthcare | Rs 1300 |
| SRL Diagnostics | Rs 1200 |
| Aarthi Scans | Rs 750 |
| Dr Lal Path Labs | Rs 1300 |
| Vijaya Diagnostics | Rs 1100 |
Prices tend to vary from one city to another. Usually, metro cities have higher prices, whereas tier 2 or tier 3 cities have lower prices. The table below lists the prices for major cities.
| City | Price |
|---|---|
| Anti TPO test cost in Delhi | Rs 600 to Rs 1300 |
| Anti TPO test cost in Gurgaon | Rs 600 to Rs 1425 |
| Anti TPO test cost in Hyderabad | Rs 595 to Rs 1400 |
| Anti TPO test cost in Chennai | Rs 595 to Rs 1300 |
| Anti TPO test cost in Mumbai | Rs 675 to Rs 1200 |
| Anti TPO test cost in Kolkata | Rs 585 to Rs 1200 |
| Anti TPO test cost in Bangalore | Rs 595 to Rs 1300 |
Thyroid disorders can be caused by multiple reasons and some other enzymes also. Thus, doctors often recommend Thyroid antibody tests, including anti-TPO and anti-TG (Thyroglobulin) tests.
Anti TPO test is a specific method for measuring thyroid antibodies. It is beneficial in patients with elevated TSH, but Free T4 levels are normal. Some of the common symptoms when you may be asked for these tests are:
There are the following purposes of the Anti-TPO antibodies test.
A doctor recommends this test when other thyroid tests like TSH, Free T3, and T4 indicate thyroid gland disorder and enlargement. Other necessary thyroid tests which doctors may recommend are
The Anti-TPO test is a simple blood test that can be taken by your doctor or at a pathology lab. The steps of the procedure are as follows:
Test results indicate the level of anti-TPO antibodies present in the blood. If it is above the normal range, it may indicate thyroid dysfunction. Your physician co-relates the result with your condition and suggests a suitable measure.
The normal range for the test is less than 60 U/ml. You may note that the normal range depends on the test method and may vary from one diagnostic centre to another. Thus, it is crucial to look for the normal range in your report and take a repeat test for treatment follow-up from the same diagnostic centre. The table below lists the normal and high range for anti-TPO antibodies.
| Range | Unit | Remark |
|---|---|---|
| Less than 60 | U/ml | Normal |
| More than 60 | U/ml | High (Above normal) |
Depending on your results, you may have a normal or high level of anti-TPO antibodies.
This signifies that antibodies are within acceptable limits. Your thyroid symptoms are probably not caused by an autoimmune disease.
It indicates a higher than acceptable level of antibodies to TPO and/or Tg (Thyroglobulin). This may mean you have an autoimmune thyroid disease. Increased levels are seen in patients with
Some people with TPO antibodies may not have thyroid disease. But their presence may increase the risk of future thyroid disorders.
Usually, autoimmune diseases require medical intervention, and you should consult your doctor.
There is minimal risk of having a blood test. You may have slight pain or bruise when the needle is inserted, but most symptoms go away quickly.
Anti TPO Test
Yes. Moderately increased thyroid peroxidase (TPO) antibodies may be found in patients with non-thyroid autoimmune diseases such as pernicious anaemia, type I diabetes, or other disorders that activate the immune system.
Thyroid disease can worsen during pregnancy. It can harm the mother and unborn baby. A pregnant thyroid disease patient may be tested for thyroid antibodies and tests involving thyroid hormone measurement.
The three types of thyroid antibodies are anti-thyroid peroxidase (TPOAb), anti-thyroglobulin antibody (TgAb), and TSH receptor antibodies (TrAb).
Dr Bhumika Rana is a Bachelor of Ayurvedic Medicine & Surgery (B.A.M.S.). Earlier She was an Operation Specialist at AIIMS Delhi & a Medical officer with the National health mission.
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